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Integrated Genomic Characterization of Papillary Thyroid

Cell, Volume 159 Issue 3, 23 October 2014, Pages 676–690

[DOI: 10.1016/j.cell.2014.09.050]


We describe the genomic landscape of papillary thyroid carcinoma (PTC), the most common type of thyroid cancer. We identify novel PTC driver mutations and perform integrated analyses of genomic variants, gene expression and DNA methylation. Our results have strong clinical implications and the potential to improve the classification of thyroid cancer and the management of patients.

Associated Data Files

These data represent a data freeze from July 14, 2013. Please note that more recent data are available via the TCGA Data Portal.

The data are supported by different organizations. All data marked by [DCC] are DCC-validated archives. All data marked by [Supplementary] were created by the manuscript authors and you should contact the corresponding author for support.

Full THCA Sample List:

BAM File list: